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        85-96 of 1772 results for 'early life'

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        Longitudinal egg-specific regulatory T- and B-cell development: Insights from primary prevention clinical trials examining the timing of egg introduction

        Egg allergy affects almost 1 in 10 Australian infants. Early egg introduction has been associated with a reduced risk in developing egg allergy; however, the immune mechanisms underlying this protection remain unclear. ...

        Research

        Nutritional Influences on Epigenetic Programming. Asthma, Allergy, and Obesity

        Reliance on increasing use of dietary supplementation and fortification (eg, with folate) to compensate for increased consumption of processed foods is also... ...

        Research

        ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity

        Experimental studies show a substantial contribution of early life environment to obesity risk through epigenetic processes. ...

        Research

        Direct infant UV light exposure is associated with eczema and immune development

        This study is the first to demonstrate an association between greater direct UV light exposures in early infancy with lower incidence of eczema ...

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        The Cardiovascular Risk Evaluation in Expectant Fathers (CARE-Dads) Study

        Susan Prescott SL MBBS BMedSci PhD FRACP Honorary Research Fellow susan.prescott@telethonkids.org.au Honorary Research Fellow Susan Prescott is a Professor of Paediatrics in the School of Medicine at the University of Western Australia. She is a ...

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        Machine Learning-Based DNA Methylation Score for Fetal Exposure to Maternal Smoking

        Fetal exposure to maternal smoking during pregnancy is associated with the development of noncommunicable diseases in the offspring. Maternal smoking may induce such long-term effects through persistent changes in the DNA methylome, which therefore hold the potential to be used as a biomarker of this early life exposure. With declining costs for measuring DNA methylation, we aimed to develop a DNA methylation score that can be used on adolescent DNA methylation data and thereby generate a score for in utero cigarette smoke exposure. ...

        Research

        The longitudinal microbial and metabolic landscape of infant cystic fibrosis: the gut-lung axis

        In cystic fibrosis, gastrointestinal dysfunction and lower airway infection occur early and are independently associated with poorer outcomes in childhood. This study aimed to define the relationship between the microbiota at each niche during the first 2 years of life, its association with growth and airway inflammation, and explanatory features in the metabolome.  ...

        Research

        In “high-risk” infants with sufficient vitamin d status at birth, infant vitamin D supplementation had no effect on allergy outcomes: A randomized controlled trial

        Early infancy oral vitamin D supplementation does not appear to reduce the development of early childhood allergic disease ...

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        Maternal serum unmetabolized folic acid concentration following multivitamin and mineral supplementation with or without folic acid after 12 weeks gestation: A randomized controlled trial

        Pregnant women are advised to take folic acid (FA) supplements before conception and during the first trimester of pregnancy. Many women continue FA supplementation throughout pregnancy, and concerns have been raised about associations between excessive FA intake and adverse maternal and child health outcomes. ...

        Research

        Prevention of Mental Health Difficulties for Children Aged 0–3 Years: A Review

        The period of infancy and early childhood is a critical time for interventions to prevent future mental health problems. The first signs of mental health difficulties can be manifest in infancy, emphasizing the importance of understanding and identifying both protective and risk factors in pregnancy and the early postnatal period. ...

        Research

        Birth outcomes and academic achievement in childhood: A population record linkage study

        This study used population-based record linkage to examine the association between early life risk factors and academic achievement. ...

        Research

        High-Fiber Diet during Pregnancy Characterized by More Fruit and Vegetable ConsumptionHigh-Fiber Diet during Pregnancy Characterized by More Fruit and Vegetable Consumption

        Higher dietary fiber intakes during pregnancy may have the potential health benefits of increasing gut microbiome diversity, lowering the risk of glucose intolerance and pre-eclampsia, achieving appropriate gestational weight gain, and preventing constipation. In this observational cohort study, we have assessed the dietary fiber intakes of 804 women in late pregnancy, using a semi-quantitative food frequency questionnaire (SQ-FFQ). Overall, the median (interquartile range) dietary fiber intake was 24.1 (19.0-29.7) grams per day (g/day). Only 237/804 (29.5%) women met the recommended Adequate Intake (AI) of dietary fiber during pregnancy of 28 g/day. ...

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