Asha Bowen AC BA MBBS DCH FRACP PhD GAICD Team Lead, Healthy Skin and ARF Prevention Team Lead, Healthy Skin and ARF Prevention Areas of expertise: Skin infections, clinical trials, Streptococcus pyogenes, Staphylococcus aureus, Aboriginal children, ...

• 1. Telethon Kids Institute
• Projects

The BCG vaccine has long been recognized for reducing the risk to suffer from infectious diseases unrelated to its target disease, tuberculosis. Evidence from human trials demonstrate substantial reductions in all-cause mortality, especially in the first week of life. Observational studies have identified an association between BCG vaccination and reduced risk of respiratory infectious disease and clinical malaria later in childhood. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021

Streptococcus pneumoniae, Moraxella catarrhalis, and nontypeable Haemophilus influenzae is associated with otitis media ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• June 2011

Christopher Hannah Peter Peter Blyth Moore Jacoby Richmond CC HC PJ PC MBBS (Hons) DCH FRACP FRCPA PhD OAM BSc (Hons) GradDipClinEpi PhD BA (Hons) MSc MBBS MRCP(UK) FRACP Director, Wesfarmers Centre of Vaccines and Infectious Diseases; Co-Head, ...

• 1. Telethon Kids Institute
• Projects
• Past projects

The aim was to document the aetiology of acute lower respiratory infection (ALRI) hospitalisations in Western Australian children ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• January 2012

Group A Streptococcus (GAS) causes pharyngitis (sore throat) and impetigo (skin sores) GAS pharyngitis triggers rheumatic fever (RF) with epidemiological evidence supporting that GAS impetigo may also trigger RF in Australian Aboriginal children. Understanding the concurrent burden of these superficial GAS infections is critical to RF prevention. This pilot study aimed to trial tools for concurrent surveillance of sore throats and skins sore for contemporary studies of RF pathogenesis including development of a sore throat checklist for Aboriginal families and pharynx photography. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• March 2023

Group A β-haemolytic Streptococcus (GAS), a Gram-positive bacterium, causes skin, mucosal and systemic infections. Repeated GAS infections can lead to autoimmune diseases acute rheumatic fever (ARF) and rheumatic heart disease (RHD). Aboriginal and Torres Strait Islander peoples in Australia have the highest rates of ARF and RHD in the world. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• March 2022

Asha Jonathan Marianne Bowen Carapetis AM Mullane AC JR MM BA MBBS DCH FRACP PhD GAICD AM MBBS FRACP FAFPHM PhD FAHMS BSc (OT) Team Lead, Healthy Skin and ARF Prevention Executive Director; Head, Strep A Translation; Co-Founder of REACH Program ...

• 1. Telethon Kids Institute
• Projects

Scabies is one of the world’s most prevalent diseases, with approximately 147 million cases at any one time and an estimated annual incidence of 455 million new episodes. Although Group A streptococcal (GAS) pharyngitis has long been implicated in the pathogenesis of acute rheumatic fever (ARF) and subsequent rheumatic heart disease (RHD), impetigo caused by GAS has recently been postulated as a link between scabies and the pathogenesis of ARF. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• October 2023

Human respiratory syncytial virus (RSV) is an important cause of acute respiratory infection with the most severe disease in the young and elderly. Non-pharmaceutical interventions and travel restrictions for controlling COVID-19 have impacted the circulation of most respiratory viruses including RSV globally, particularly in Australia, where during 2020 the normal winter epidemics were notably absent. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• May 2022

Immunity is distinct in early life and greater precision is required in our understanding of mechanisms of early life protection to inform development of new pediatric vaccines ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• April 2020

The global population has been severely affected by the coronavirus disease 2019 (COVID-19) pandemic, however, with older age identified as a risk factor, children have been underprioritized. This article discusses the factors contributing to the less severe response observed in children following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including, differing viral entry receptor expression and immune responses. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• May 2023