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        Goroka Otitis Media Study: Prevalence and associated risk factors of otitis media in children attending urban clinics in Goroka, Eastern Highlands Province of Papua New Guinea

        Deborah Chris Tamara Lehmann Brennan-Jones Veselinovic D C TV AO, MBBS, MSc PhD MClinAud Honorary Emeritus Fellow Head, Ear Health Clinical Research Officer/PhD student chris.brennan-jones@telethonkids.org.au tamara.veselinovic@telethonkids.org.au ...

        Research

        Elevated IL-5 and IL-13 responses to egg proteins predate the introduction of egg in solid foods in infants with eczema

        Elevated egg-specific Th2 cytokine responses were established prior to egg ingestion at 4months and were not significantly altered by introduction of egg ...

        Research

        The genetic associations of acute anterior uveitis and their overlap with the genetics of ankylosing spondylitis

        These findings also suggest that variants in ERAP1 have a differential impact on the risk of AAU when compared with AS, and hence the genetic risk for AAU... ...

        Research

        Clinical development strategy for a candidate group A streptococcal vaccine

        This review outlines a clinical development strategy detailing the phases of development required for registration of a candidate Group A streptococci vaccin ...

        Research

        Long-term outcomes from acute rheumatic fever and rheumatic heart disease

        Adverse outcomes for people with acute rheumatic fever and rheumatic heart disease and the effect of comorbidities and demographic factors on these outcomes ...

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        Early Nutrition as a Major Determinant of 'Immune Health': Implications for Allergy, Obesity and Other Noncommunicable Diseases

        A better understanding of nutritional programming of immune health may lead to dietary strategies that reduce the burden of many inflammatory diseases ...

        Research

        Evolution, Evidence and Effect of Secondary Prophylaxis Against Rheumatic Fever

        The association between group A streptococcal infection and rheumatic fever (RF) was established in the early 20th century. ...

        Research

        Assessment of cardiometabolic risk in children in population studies: underpinning developmental origins of health and disease mother–offspring cohort studies

        Pregnancy and birth cohorts have been utilised extensively to investigate the developmental origins of health and disease, particularly in relation to... ...

        Research

        Rheumatic heart disease in Indigenous children in northern Australia: Differences in prevalence and the challenges of screening

        This study compared regional differences in the prevalence of rheumatic heart disease in Indigenous Australian children, and describes the logistical and... ...

        Research

        The role of PKCzeta in cord blood T-cell maturation towards Th1 cytokine profile and its epigenetic regulation by fish oil

        Here, we present evidence that there are two major control points to explain the immunodeficiency in CB T-cells, leading to a decreased IFNy synthesis. ...

        Research

        Influence of maternal obesity on the long-term health of offspring

        Including immediate implications for pregnancy complications, increasing evidence implicates maternal obesity having a major impact on long term child health. ...

        Research

        Pneumococcal conjugate vaccines PREVenar13 and SynflorIX in sequence or alone in high-risk indigenous infants (PREV-IX-COMBO)

        Otitis media (OM) starts within weeks of birth in almost all Indigenous infants living in remote areas of the Northern Territory (NT). ...

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