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        Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape

        Respiratory syncytial virus is the second most common cause of infant mortality and a major cause of morbidity and mortality in older adults (aged >60 years). Efforts to develop a respiratory syncytial virus vaccine or immunoprophylaxis remain highly active. ...

        Research

        Effectiveness of 13-valent pneumococcal conjugate vaccine against hypoxic pneumonia and hospitalisation in Eastern Highlands Province, Papua New Guinea: An observational cohort study

        Pneumonia is a leading cause of childhood mortality with Streptococcus pneumoniae a major contributor. Pneumococcal conjugate vaccines (PCVs) have been introduced into immunisation programs in many low- to middle-income countries yet there is a paucity of data evaluating the effectiveness in these settings. We assess the effectiveness of 13-valent PCV against hypoxic pneumonia, hospitalisation and other clinical endpoints in children <5 years living in Eastern Highlands Province, Papua New Guinea). ...

        Research

        Molecular-genetic profiling and high-throughput in vitro drug screening in NUT midline carcinoma-An aggressive and fatal disease

        Our data emphasize the heterogeneity of NMC and highlights genetic aberrations that could be explored to improve therapeutic strategies. ...

        Research

        Method of bacterial killing differentially affects the human innate immune response to Staphylococcus epidermidis

        In vitro investigations of human innate immune responses to extracellular bacteria commonly utilise killed preparations in preference to live organisms ...

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        Assistance and Companion Dogs for children diagnosed with Autism Spectrum Disorder and Fragile X

        Andrew Gail Whitehouse Watch and listen to Andrew Alvares AJ GA PhD PhD Angela Wright Bennett Professor of Autism Research at Telethon Kids and University of Western Australia; Director, CliniKids Senior Research Fellow 08 6319 1698 ...

        Research

        Computational fluid-particle dynamic and pharmacokinetic assessment of electronic cigarette aerosols for improved understanding of their potential to impact health

        Alexander Larcombe A BScEnv (Hons) PhD Team Leader, Respiratory Environmental Health Team Leader, Respiratory Environmental Health Associate Professor Alexander Larcombe began work at the Telethon Institute in 2005 and is now a Senior Research ...

        Research

        Defining target penicillin concentrations for subsequent studies of a reformulated long-acting benzathine penicillin prototype

        Jonathan Tim Carapetis AM Barnett JR TB AM MBBS FRACP FAFPHM PhD FAHMS PhD Executive Director; Head, Strep A Translation; Co-Founder of REACH Head of the Strep A Pathogenesis & Diagnostics team, Deputy Director of the Wesfarmers Centre of Vaccines ...

        Research

        A randomised-controlled trial of a parent-mediated intervention for managing uncertainty in young children diagnosed on the autism spectrum

        Gail Andrew Alvares Whitehouse Watch and listen to Andrew GA AJ PhD PhD Senior Research Fellow Angela Wright Bennett Professor of Autism Research at Telethon Kids and University of Western Australia; Director, CliniKids 08 6319 1698 gail.alvares@ ...

        Research

        Acceptability of sonicated versus unsonicated reconstituted (powdered) benzathine penicillin G for rheumatic fever prophylaxis

        Jonathan Carapetis AM JR AM MBBS FRACP FAFPHM PhD FAHMS Executive Director; Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@telethonkids.org.au Institute Director; Head, Strep A Translation; Co-Founder of REACH Professor ...

        Research

        Evidence against poor semantic encoding in individuals with autism

        This article tests the hypothesis that individuals with autism poorly encode verbal information to the semantic level of processing, instead paying greater... ...

        Research

        Utilising Behavioural and Sensory Profiles and Associated Perinatal Factors to Identify Meaningful Subgroups in Autism Spectrum Disorder

        The heterogeneity of autism spectrum disorder clinically and aetiologically hinders intervention matching and prediction of outcomes. This study investigated if the behavioural, sensory, and perinatal factor profiles of autistic children could be used to identify distinct subgroups. Participants on the autism spectrum aged 2 to 17 years and their families were sourced via the Australian Autism Biobank. ...

        Research

        Brief Report: Do the Nature of Communication Impairments in Autism Spectrum Disorders Relate to the Broader Autism Phenotype in Parents?

        This research explored the relationship between the broader autism phenotype (BAP) among parents, an index of genetic liability for ASD, and proband... ...

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