Including immediate implications for pregnancy complications, increasing evidence implicates maternal obesity having a major impact on long term child health. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• January 2017

This paper discusses the rising prevalence of allergic disease in children. This review article considers recent findings in the field of paediatric immune... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• October 2015

This review article examines the evidence of the impact of in utero and postnatal vitamin D exposure on allergy risk in childhood ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• December 2014

The dramatic rise in allergic disease has occurred in tandem with recent environmental changes and increasing indoor lifestyle culture. While multifactorial, one consistent allergy risk factor has been reduced sunlight exposure. However, vitamin D supplementation studies have been disappointing in preventing allergy, raising possible independent effects of ultraviolet (UV) light exposure. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• May 2021

As we discuss, equal weekly visits to major fast-food outlets by the affluent and deprived do not translate into biological equivalency. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017

ATP Binding Cassette Subfamily A Member 3 (ABCA-3) is a lipid transporter protein highly expressed in type-II alveolar (AT-II) cells. Mutations in ABCA3 can result in severe respiratory disease in infants and children. To study ABCA-3 deficiency in vitro, primary AT-II cells would be the cell culture of choice although sample accessibility is limited. Our aim was to investigate the suitability of primary nasal epithelial cells, as a surrogate culture model for AT-II cells, to study ABCA-3 deficiency. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• February 2022

These results show that a word gap related to maternal education is not apparent up to twelve months of age ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• February 2020

The Secret Life of Your Microbiome shatters this deeply held myth, presenting a revolutionary new paradigm, backed by vast science ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• January 2017

The extent of lung hypoplasia impacts the survival and severity of morbidities associated with congenital diaphragmatic hernia. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

Pulmonary exacerbations in cystic fibrosis are characterized by airway inflammation and may cause irreversible lung damage. Early identification of such exacerbations may facilitate early initiation of treatment, thereby potentially reducing long-term morbidity. Research question: Is it possible to predict pulmonary exacerbations in children with cystic fibrosis, using inflammatory markers obtained from BAL fluid? ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• December 2020

A standardised framework for selecting outcomes for evaluation in trials has been proposed by the Core Outcome Measures in Effectiveness Trials working group. However, this method does not specify how to ensure that the outcomes that are selected are causally related to the disease and the health intervention being studied. Causal network diagrams may help researchers identify outcomes that are both clinically meaningful and likely to be causally dependent on the intervention, and endpoints that are, in turn, causally dependent on those outcomes. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• October 2021

The effects of maternal alcohol-use disorder are experienced by the majority of exposed children rather than a vulnerable subgroup of this population ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• March 2020