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        1045-1056 of 1360 results for '2018'

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        Molecular Epidemiology of Noninvasive and Invasive Group A Streptococcal Infections in Cape Town

        There is low coverage of the multivalent M protein vaccine in our setting, emphasizing the need to reformulate the vaccine to improve coverage ...

        Research

        The importance of the exposome and allostatic load in the planetary health paradigm

        The concept of planetary health emphasizes that human health is intricately connected to the health of natural systems within the Earth's biosphere ...

        Research

        Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma

        We report clinical, radiologic, and molecular factors that correlate with survival in children and young adults with diffuse intrinsic pontine glioma ...

        Research

        Lessons learned in the development of sustained release penicillin drug delivery systems for the prophylactic treatment of rheumatic heart disease (RHD)

        The current prophylactic treatment to prevent rheumatic heart disease requires four-weekly intramuscular injection of a suspension of the poorly soluble benzathine salt form of penicillin G (BPG) often for more than 10 years. In seeking to reduce the frequency of administration to improve adherence, biodegradable polymer matrices have been investigated. ...

        Research

        Time to tackle rheumatic heart disease: Data needed to drive global policy dialogues

        This report provides an update on the contemporary global and regional policy landscapes relevant to rheumatic heart disease ...

        Research

        Severe lower limb cellulitis: Defining the epidemiology and risk factors for primary episodes in a population-based case-control study

        Severe lower leg cellulitis presents a major burden to the health sector and is increasing with an ageing population ...

        Research

        Epidemiology and risk factors for recurrent severe lower limb cellulitis: a longitudinal cohort study

        Severe lower leg cellulitis recurrences are frequent, and each episode increases the likelihood of subsequent recurrence and length of hospitalization ...

        Research

        Can polymorphisms in the fatty acid desaturase (FADS) gene cluster alter the effects of fish oil supplementation on plasma and erythrocyte fatty acid profiles?

        Supplementation with fish oil may only significantly increase DHA in minor allele carriers of FADS1 SNPs ...

        Research

        Potential for molecular testing for group a streptococcus to improve diagnosis and management in a high-risk population: A prospective study

        Implementation of molecular testing could improve antibiotic use in this high-burden setting ...

        Research

        HLA-DR Class II expression on myeloid and lymphoid cells in relation to HLA-DRB1 as a genetic risk factor for visceral leishmaniasis

        To understand how HLA-DR contributes to disease pathogenesis, we examined expression at the protein level in circulating myeloid and lymphoid cells of VL patients ...

        Research

        Determinants for progression from asymptomatic infection to symptomatic visceral leishmaniasis: A cohort study

        We confirmed the strong association between high DAT and/or rK39 titers and progression to disease among asymptomatic subjects ...

        Research

        The relationship between Bordetella pertussis genotype and clinical severity in Australian children with pertussis

        In children, we found no relationship between Prn status and markers of severe pertussis ...

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