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        1057-1068 of 1360 results for '2018'

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        Infection Transmission in Early Childhood Education and Care: a mixed methods study to inform future interventions

        Rebecca Hayley Hannah Christopher Pavlos Christian Moore Blyth RP HC HC CC PhD, MSFS, BSc (1st Class Hons), PhD W.Aust. OAM BSc (Hons) GradDipClinEpi PhD MBBS (Hons) DCH FRACP FRCPA PhD Senior Program Manager Program Head, Healthy Behaviours and ...

        Research

        Prediction of Causative Pathogen of Osteomyelitis Using Bayesian Network Modelling

        Asha Christopher Tom Bowen Blyth Snelling AC CC T BA MBBS DCH FRACP PhD GAICD OAM MBBS (Hons) DCH FRACP FRCPA PhD BMBS DTMH GDipClinEpid PhD FRACP Head, Healthy Skin and ARF Prevention Centre Head, Wesfarmers Centre of Vaccines and Infectious ...

        Research

        Water Quality and the Microbiome Study (TUMS): The effects of chlorinated drinking water on the assembly of the infant gut microbiome

        David Debbie Desiree Matt Susan Martino Palmer Silva Cooper Prescott DM D DS MC SL BSc PhD BSc BND PhD MBBS, FRACP, MPH, PhD BCA Marketing, BSc Statistics and Applied Statistics, PhD MBBS BMedSci PhD FRACP Head, Clinical Epigenetics Head, Early Life ...

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        The STAMP RSV Program

        Hannah Christopher Samantha Minda Moore Blyth Carlson Sarna HC CC SC MS OAM BSc (Hons) GradDipClinEpi PhD MBBS (Hons) DCH FRACP FRCPA PhD BSc MPH PhD M.App.Epid., PhD Program Head, Infection and Vaccines Centre Head, Wesfarmers Centre of Vaccines ...

        Research

        Associations between the human immune system and gut microbiome with neurodevelopment in the first 5 years of life: A systematic scoping review

        The aim of this review was to map the literature assessing associations between maternal or infant immune or gut microbiome biomarkers and child neurodevelopmental outcomes within the first 5 years of life. We conducted a PRISMA-ScR compliant review of peer-reviewed, English-language journal articles. ...

        Research

        Defining the pediatric response to SARS-CoV-2 variants

        The global population has been severely affected by the coronavirus disease 2019 (COVID-19) pandemic, however, with older age identified as a risk factor, children have been underprioritized. This article discusses the factors contributing to the less severe response observed in children following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including, differing viral entry receptor expression and immune responses. ...

        Research

        Skin health situational analysis to inform skin disease control programs for the Kimberley

        Marianne John Rebecca Stephanie Asha Jonathan Mullane Jacky Pavlos Enkel Bowen Carapetis AM MM JJ RP SE AC JR BSc (OT) PhD, MSFS, BSc (Hons), MPH, MIPH BA MBBS DCH FRACP PhD GAICD OAM AM MBBS FRACP FAFPHM PhD FAHMS Program Advisor, SToP Trial ...

        Research

        Where are the alcohol advertising hotspots near schools?

        Physically locating liquor stores near schools can strongly influence the chances of youth accessing and consuming alcohol, and may also increase children's exposure to alcohol advertising. Investigating the association between the presence of a liquor store near a school and the prevalence of outdoor alcohol advertising is crucial from a policy perspective, as it can inform future regulations on the placement of liquor stores and outdoor advertising near educational institutions.  ...

        Research

        A Review of Cardiac Surgical Procedures and Their Outcomes for Paediatric Rheumatic Heart Disease in Western Australia

        Surgical intervention is an important treatment modality for advanced rheumatic heart disease (RHD). This study aimed to describe patient characteristics and outcomes from cardiac surgery for RHD in patients referred to the only tertiary paediatric hospital in Western Australia.  ...

        Research

        ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma

        Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPG), are the most lethal of childhood cancers. Palliative radiotherapy is the only established treatment, with median patient survival of 9 to 11 months. ONC201 is a DRD2 antagonist and ClpP agonist that has shown preclinical and emerging clinical efficacy in DMG.  ...

        Research

        Modeling COVID-19 disease processes by remote elicitation of causal Bayesian networks from medical experts

        COVID-19 is a new multi-organ disease causing considerable worldwide morbidity and mortality. While many recognized pathophysiological mechanisms are involved, their exact causal relationships remain opaque. Better understanding is needed for predicting their progression, targeting therapeutic approaches, and improving patient outcomes. While many mathematical causal models describe COVID-19 epidemiology, none have described its pathophysiology. ...

        Research

        Patient-reported outcome measures for paediatric acute lower respiratory infection studies

        Patient-reported outcome measures (PROMs) are recommended for capturing meaningful outcomes in clinical trials. The use of PROMs for children with acute lower respiratory infections (ALRIs) has not been systematically reported. We aimed to identify and characterise patient-reported outcomes and PROMs used in paediatric ALRI studies and summarise their measurement properties. ...

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