The aim of this study was to examine the influence of smoking in pregnancy on child and adolescent behavioural development, in comparison with mothers who cease ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• July 2010

The goals were to compare the fracture incidence in Rett syndrome with that in the general population and to investigate the impact of genotype, epilepsy,... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2008
• March 2008

Evidence about the association between maternal mental health disorders and stillbirth and infant mortality is limited and conflicting. We aimed to examine whether maternal prenatal mental health disorders are associated with stillbirth and/or infant mortality. MEDLINE, Embase, PsycINFO, and Scopus were searched for studies examining the association of any maternal prenatal (occurring before or during pregnancy) mental health disorder(s) and stillbirth or infant mortality. A random-effects meta-analysis was used to calculate pooled odds ratios (ORs) with 95% confidence intervals (CIs). The between-study heterogeneity was quantified using the I2 statistic. Subgroup analyses were performed to identify the source of heterogeneity. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

Chorioamnionitis is a common antecedent of preterm birth and induces inflammation and oxidative stress in the fetal lungs. Reducing inflammation and oxidative stress in the fetal lungs may improve respiratory outcomes in preterm infants. Creatine is an organic acid with known anti-inflammatory and antioxidant properties. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• July 2024

Inhaled allergens are known for their immediate and ongoing effects in the respiratory tract (RT). ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• August 2010

One explanation for the high burden of allergic and autoimmune diseases in industrialized countries is inappropriate immune development under modern... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• November 2012

Lung clearance index may be a useful surveillance tool to monitor structural lung disease in preschool and school-age children with cystic fibrosis ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Bacillus cereus can cause serious infections in immunosuppressed patients. This population may be susceptible to B. cereus pneumonia, bacteremia, cellulitis,... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• April 2013

Previous genome-wide association studies revealed multiple common variants involved in eczema but the role of rare variants remains to be elucidated. Here, we investigate the role of rare variants in eczema susceptibility. We meta-analyze 21 study populations including 20,016 eczema cases and 380,433 controls. Rare variants are imputed with high accuracy using large population-based reference panels. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

Lung damage in children with CF occurs much earlier than previously thought, and proving this is related to the decline that occurs later will create new paradigms for prevention and treatment. ...

• 1. Telethon Kids Institute
• Projects

Reviewed in this article these studies have identified positive association at 21 genes with association at five of these replicated in independent populations. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• March 2012

The hallmark of atopic asthma is transient airways hyperresponsiveness (AHR) preceded by aeroallergen-induced Th-cell activation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• January 2011