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        97-108 of 115 results for 'Professor Stephen Stick'

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        Airway epithelial repair in health and disease: Orchestrator or simply a player?

        This review attempts to highlight migration-specific and cell-extracellular matrix (ECM) aspects of repair used by epithelial cells ...

        Research

        Regional Differences in Susceptibiity of Bronchial Epithelium to Mesenchymal Transition and Inhibition by the Macrolide Antibiotic Azithromycin

        Dysregulated repair following epithelial injury is a key forerunner of disease in many organs, and the acquisition of a mesenchymal phenotype by the injured... ...

        Research

        DNA Methylation Profiles of Airway Epithelial Cells and PBMCs from Healthy, Atopic and Asthmatic Children

        Allergic inflammation is commonly observed in a number of conditions that are associated with atopy including asthma, eczema and rhinitis. ...

        Research

        Hypoxia and sterile inflammation in cystic fibrosis airways: Mechanisms and potential therapies

        In this review, we consider recent evidence regarding hypoxia and sterile inflammation in cystic fibrosis airways ...

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        Alpha-1 antitrypsin mitigates the inhibition of airway epithelial cell repair by neutrophil elastase

        Free NE activity is deleterious for epithelial homeostasis and support the hypothesis that proteases in the airway contribute to CF structural lung disease ...

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        Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability

        HRV-1B infection directly alters human airway epithelial TJ expression leading to increased epithelial permeability potentially via antiviral response of IL-15 ...

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        Assessment of p.Phe508del-CFTR functional restoration in pediatric primary cystic fibrosis airway epithelial cells

        This study assessed an alternative approach, using a small scale halide assay that can be adapted for a personalized high throughput setting to analyze CFTR function of pAEC. ...

        Research

        Development and validation of a miniaturized bacteriophage host range screening assay against antibiotic resistant Pseudomonas aeruginosa

        Antimicrobial resistance is a current global health crisis, and the increasing emergence of multidrug resistant infections has led to the resurgent interest in bacteriophages as an alternative treatment. ...

        Research

        Disruption of β-catenin/CBP signaling inhibits human airway epithelial-mesenchymal transition and repair.

        The airway epithelium of both children and adults with asthma is relatively undifferentiated characterized by a significantly increased proportion of... ...

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        Rhinovirus Infection Is Associated With Airway Epithelial Cell Necrosis and Inflammation via Interleukin-1 in Young Children With Cystic Fibrosis

        This study found rhinovirus infection drives necrotic cell death in cystic fibrosis airway epithelial cells ...

        Research

        Azithromycin Partially Mitigates Dysregulated Repair of Lung Allograft Small Airway Epithelium

        Chronic airway injury and dysregulated repair programs are evident in airway epithelium obtained from patients with bronchiolitis obliterans syndrome ...

        Research

        COCOON: Virus transmission, immunity, and family wellbeing during COVID-19

        Asha Desiree Stephen Susan Bowen Silva Stick Prescott AC DS SM SL BA MBBS DCH FRACP PhD GAICD OAM MBBS, FRACP, MPH, PhD MB BChir PhD MRCP FRACP MBBS BMedSci PhD FRACP Head, Healthy Skin and ARF Prevention Co-Head, The ORIGINS Project Head, P4 ...

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