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        Influence of maternal obesity on the long-term health of offspring

        Increasing evidence implicates maternal obesity as a major determinant of offspring health during childhood and later adult life ...

        Research

        Can polymorphisms in the fatty acid desaturase (FADS) gene cluster alter the effects of fish oil supplementation on plasma and erythrocyte fatty acid profiles? An exploratory study

        Overall results of this preliminary study suggest that supplementation with fish oil may only significantly increase DHA in minor allele carriers of FADS1 SNPs. Further research is required to confirm this novel finding. ...

        Research

        Fish oil supplementation in early infancy modulates developing infant immune responses

        Maternal fish oil supplementation during pregnancy has been associated with altered infant immune responses and a reduced risk of infant sensitization and... ...

        Research

        Effect of sitting posture on development of scoliosis in duchenne muscular dystrophy cases

        This study assessed the contribution of physical factors including lumbar posture to scoliosis in non-ambulatory youth with DMD in Nepal. ...

        Research

        Transforming Life: A Broad View of the Developmental Origins of Health and Disease Concept from an Ecological Justice Perspective

        With emerging research involving green space, the microbiome, biodiversity and positive psychology, we discuss ecological justice in the dysbiosphere ...

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        How Well Does the EQ-5D-Y-5L Describe Children With Intellectual Disability?: “There's a Lot More to My Child Than That She Can't Wash or Dress Herself.”

        The EQ-5D-5L is a generic health utility instrument for measuring health-related quality of life (HRQoL), with self-report and proxy report versions for children (EQ-5D-Y-5L). Children with intellectual disability (ID) are a heterogeneous population whose impairments and comorbidities place them at risk of poor HRQoL. This study aimed to describe the content validity and suitability for children with ID of a proxy report version of the EQ-5D-Y-5L as seen by their caregivers. ...

        Research

        Sleep-disordered breathing in Australian children with Prader-Willi syndrome following initiation of growth hormone therapy

        In children with Prader-Willi syndrome (PWS), growth hormone (GH) improves height and body composition; however, may be associated with worsening sleep-disordered breathing (SDB). Some studies have reported less SDB after GH initiation, but follow-up with polysomnography is still advised in most clinical guidelines. ...

        Research

        Systematic analysis of transcription start sites in avian development

        CAGE in combination with single-molecule sequencing technology allows mapping of TSSs and genome-wide capture of promoter activities state cell populations. ...

        Research

        Down to Earth: Planetary Health and Biophilosophy in the Symbiocene Epoch

        Advances in science have illuminated the role of the “ecological theatre”—the total living environment—in human health ...

        Research

        The role of PKCzeta in cord blood T-cell maturation towards Th1 cytokine profile and its epigenetic regulation by fish oil

        Here, we present evidence that there are two major control points to explain the immunodeficiency in CB T-cells, leading to a decreased IFNy synthesis. ...

        Research

        Influence of maternal obesity on the long-term health of offspring

        Including immediate implications for pregnancy complications, increasing evidence implicates maternal obesity having a major impact on long term child health. ...

        Research

        Early Nutrition as a Major Determinant of 'Immune Health': Implications for Allergy, Obesity and Other Noncommunicable Diseases

        A better understanding of nutritional programming of immune health may lead to dietary strategies that reduce the burden of many inflammatory diseases ...

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