Lung damage in children with CF occurs much earlier than previously thought, and proving this is related to the decline that occurs later will create new paradigms for prevention and treatment. ...

• 1. Telethon Kids Institute
• Projects

The constant-phase model (CPM) is commonly fit to respiratory system input impedance (Z rs) to estimate lung mechanics. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• November 2012

To assess the determinants of early lung function in African infants. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• May 2017

Graham Rachel Hall Foong GL RF BAppSci PhD CRFS FANZSRS FThorSoc FERS BSc (hons), PhD, MBiostat Honorary Research Associate Senior Research Fellow 08 6319 1626 Rachel.Foong@telethonkids.org.au Honorary Research Associate Senior Research Fellow ...

• 1. Telethon Kids Institute
• Projects

The major morbidity and mortality from cystic fibrosis (CF) comes from progressive lung disease with bronchiectasis leading to respiratory failure ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• January 2011

Among Aboriginal children, the burden of acute respiratory tract infections (ALRIs) with consequent bronchiectasis post-hospitalisation is high. Clinical practice guidelines recommend medical follow-up one-month following discharge, which provides an opportunity to screen and manage persistent symptoms and may prevent bronchiectasis. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• October 2021

This paper is an introduction to a series of articles about improved measurement of lung function in patients with chronic lung disease. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• June 2014

The aim of this study was to assess whether in utero tobacco smoke exposure alone affects early-life lung growth and development. Pregnant BALB/c mice... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• February 2011

The lung clearance index may be a useful surveillance tool for monitoring the presence and extent of lower airway inflammation and infection ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• September 2017

Children born preterm have impaired lung function and altered lung structure. However, there are conflicting reports on how preterm birth impacts aerobic exercise capacity in childhood. We aimed to investigate how neonatal history and a diagnosis of bronchopulmonary dysplasia (BPD) impact the relationship between function and structure of the lung, and aerobic capacity in school-aged children born very preterm. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• February 2021

In the Saline Hypertonic in Preschoolers (SHIP) study, inhaled 7% hypertonic saline improved the lung clearance index in children aged 3-6 years with cystic fibrosis, but it remained unclear whether improvement is also seen in structural lung disease. We aimed to assess the effect of inhaled hypertonic saline on chest CT imaging in children aged 3-6 years with cystic fibrosis. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• March 2022

Measurement of lung volumes across the life course is critical to the diagnosis and management of lung disease. The aim of the study was to use the Global Lung Function Initiative methodology to develop all-age multi-ethnic reference equations for lung volume indices determined using body plethysmography and gas dilution techniques. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• March 2021