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        Patterns of sensory modulation by age and sex in young people on the autism spectrum

        Sensory modulation symptoms form a diagnostic criterion for autism spectrum disorder and are associated with significant daily functional limitations. Utilizing caregiver report on Short Sensory Profile-2 (SSP-2) for 919 autistic children (3–14.11 years), we examined the expression of sensory modulation symptoms by age and sex and investigated the existence of specific sensory modulation subtypes. ...

        Research

        Implications of providing wrist-hand orthoses for children with cerebral palsy: evidence from a randomised controlled trial

        To investigate the effects of providing rigid wrist-hand orthoses plus usual multidisciplinary care, on reducing hand impairments in children with cerebral palsy. ...

        Research

        Geographical Differences and Temporal Improvements in Forced Expiratory Volume in 1 Second of Preterm-Born Children: A Systematic Review and Meta-analysis

        Although preterm birth is associated with later deficits in lung function, there is a paucity of information on geographical differences and whether improvements occur over time, especially after surfactant was introduced. ...

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        Spatio-temporal monitoring of health facility-level malaria trends in Zambia and adaptive scaling for operational intervention

        The spatial and temporal variability inherent in malaria transmission within countries implies that targeted interventions for malaria control in high-burden settings and subnational elimination are a practical necessity. Identifying the spatio-temporal incidence, risk, and trends at different administrative geographies within malaria-endemic countries and monitoring them in near real-time as change occurs is crucial for developing and introducing cost-effective, subnational control and elimination intervention strategies. ...

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        Haemolysis Detection in MicroRNA-Seq from Clinical Plasma Samples

        The abundance of cell-free microRNA (miRNA) has been measured in blood plasma and proposed as a source of novel, minimally invasive biomarkers for several diseases. Despite improvements in quantification methods, there is no consensus regarding how haemolysis affects plasma miRNA content. ...

        Research

        Influenza vaccination among pregnant women in two hospitals in Sydney, NSW: what we can learn from women who decline vaccination

        Pregnant women are recognised as being at risk of serious illness from influenza. Despite this, and longstanding national recommendations for vaccination in pregnancy, vaccine uptake remains suboptimal. This study aims to determine factors associated with women declining influenza vaccination in pregnancy. ...

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        Neuroanatomical heterogeneity and homogeneity in individuals at clinical high risk for psychosis

        Individuals at Clinical High Risk for Psychosis (CHR-P) demonstrate heterogeneity in clinical profiles and outcome features. However, the extent of neuroanatomical heterogeneity in the CHR-P state is largely undetermined. ...

        Research

        COVID-19 Vaccine Mandates: Attitudes and Effects on Holdouts in a Large Australian University Population

        Many governments and institutions mandated COVID-19 vaccines. In late 2021, we sought to ascertain the perspectives of staff and students from The University of Western Australia about the State or the University mandating COVID-19 vaccines. ...

        Research

        Flexible societies excelled in saving lives in the first phase of the COVID-19 pandemic

        Previous studies have shown that national cultural traits, such as collectivism–individualism and tightness–looseness, are associated with COVID-19 infection and mortality rates. ...

        Research

        Not in employment, education or training (NEET); more than a youth policy issue

        Australians who are Not in Employment, Education or Training (NEET) and receive income support span a wide spectrum of working ages. Australian research has concentrated on NEETs aged 15-29 years, in line with international standards. This paper investigates extending the NEET concept to include all working age persons 15-64 years and the value added to welfare policy through analysis of a new linked dataset. ...

        Research

        Leading excellence through equity: Social emotional learning for a Fair Go

        Australia likes to call itself the land of the "Fair Go". But what does a Fair Go mean for students from backgrounds of deep disadvantage? The UN Sustainable Development Goals for 2030 aim to ensure "inclusive and equitable quality education and [to promote] lifelong learning opportunities for all" (United Nations, 2015). ...

        Research

        Defining the fetal origin of MLL-AF4 infant leukemia highlights specific fatty acid requirements

        Infant MLL-AF4-driven acute lymphoblastic leukemia (ALL) is a devastating disease with dismal prognosis. A lack of understanding of the unique biology of this disease, particularly its prenatal origin, has hindered improvement of survival. We perform multiple RNA sequencing experiments on fetal, neonatal, and adult hematopoietic stem and progenitor cells from human and mouse. ...

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