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        Preliminary consultation on preferred product characteristics of benzathine penicillin G for secondary prophylaxis of rheumatic fever

        A sample target product profile for reformulated benzathine penicillin G is presented ...

        Research

        Addressing the challenges of cross-jurisdictional data linkage between a national clinical quality registry and government-held health data

        Describing the challenges of obtaining state and nationally held data for linkage to a non-government national clinical registry ...

        Research

        Improving cardiovascular outcomes among Aboriginal Australians: Lessons from research for primary care

        Primary care practitioners have an important role in improving Aboriginal cardiovascular care outcomes ...

        Research

        Sulfamethoxazole-Trimethoprim (Cotrimoxazole) for Skin and Soft Tissue Infections Including Impetigo, Cellulitis, and Abscess

        We conducted a systematic review of clinical trials and observational studies that address the utility of SXT for SSTI treatment, caused by either GAS or MRSA ...

        Research

        Genome-Wide Analysis of Genetic Risk Factors for Rheumatic Heart Disease in Aboriginal Australians Provides Support for Pathogenic Molecular Mimicry

        Rheumatic heart disease (RHD) after group A streptococcus (GAS) infections is heritable and prevalent in Indigenous populations. Molecular mimicry between human and GAS proteins triggers proinflammatory cardiac valve-reactive T cells. ...

        Research

        The prevention, diagnosis and management of central venous line infections in children

        With advancing paediatric healthcare, the use of central venous lines has become a fundamental part of management of neonates and children. ...

        Research

        Are minor echocardiographic changes associated with an increased risk of acute rheumatic fever or progression to rheumatic heart disease?

        We aimed to determine the significance of minor heart valve abnormalities, including Borderline RHD, in predicting the future risk of acute rheumatic fever. ...

        Research

        Clinical practice guidelines: Their utility, dissemination and monitoring at Colonial War Memorial Hospital: A mixed methods study from Fiji

        Clinical practice guidelines (CPGs) improve patient care by standardising medical practice. However, little is known about their applicability in low-resource settings. Since 2010, Fiji has introduced guidelines to increase the application of evidence-based practice. ...

        Research

        Population pharmacokinetic study of benzathine penicillin G administration in Indigenous children and young adults with rheumatic heart disease in the Northern Territory, Australia

        Benzathine penicillin G is the cornerstone of secondary prophylaxis to prevent Streptococcus pyogenes infections, which precede acute rheumatic fever. ...

        Research

        Development of methods to rapidly track pathogen and antibiotic resistance profiles from skin sores in Northern Australia (Hot North)

        Asha Jonathan Marianne Tim Bowen Carapetis AM Mullane Barnett AC JR MM TB BA MBBS DCH FRACP PhD GAICD AM MBBS FRACP FAFPHM PhD FAHMS BSc (OT) PhD Team Lead, Healthy Skin and ARF Prevention Executive Director; Head, Strep A Translation; Co-Founder of ...

        Research

        END RHD Community Project - Kimberley (Rheumatic Fever Strategy)

        Dylan John Jonathan Rosemary Barth Jacky Carapetis AM Wyber DB JJ JR R B.Tech, MPH, PhD AM MBBS FRACP FAFPHM PhD FAHMS MBChB MPH FRACGP PhD Postdoctoral Research Fellow / Epidemiologist Community Researcher Executive Director; Head, Strep A ...

        Research

        Honey as a potential topical treatment for skin infections: a literature review

        Asha Glenn Marianne Bowen Pearson Mullane AC G MM BA MBBS DCH FRACP PhD GAICD BA (Education) PhD Candidate BSc (OT) Team Lead, Healthy Skin and ARF Prevention Director of First Nations Strategy and Leadership Program Advisor, SToP Trial ...

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