T-cell lymphoblastic lymphoma (T-LBL) is a rare and aggressive lymphatic cancer, often diagnosed at a young age. Patients are treated with intensive chemotherapy, potentially followed by a hematopoietic stem cell transplantation. Although prognosis of T-LBL has improved with intensified treatment protocols, they are associated with side effects and 10-20% of patients still die from relapsed or refractory disease. Given this, the search toward less toxic anti-lymphoma therapies is ongoing. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• January 2023

Sensitivity and positive predictive value of cardiac auscultation compared with echocardiography is poor, regardless of the expertise of the auscultator. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• August 2013

We conducted a comprehensive, systematic review of the global childhood population prevalence of impetigo and the broader condition pyoderma. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• August 2015

We aimed to measure the incidence and severity of invasive Group A Strep disease in the NT since 1996. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• January 2014

IgE antibodies in house dust mite (HDM) allergy follow a predictable pattern. Half are directed against two dominant allergens and the remainder largely against ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• July 2010

Aberrant expression of the TLX1/HOX11 proto-oncogene is associated with a significant subset of T-cell acute lymphoblastic leukemias... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• March 2010

Following the introduction of jurisdictional maternal pertussis vaccination programs in Australia, we estimated maternal vaccine effectiveness (VE) and whether maternal pertussis vaccination modified the effectiveness of the first 3 primary doses of pertussis-containing vaccines. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• November 2023

To evaluate the effectiveness of maternal pertussis vaccination for preventing pertussis infections in Aboriginal and Torres Strait Islander infants under seven months of age. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• February 2024

In this study, we investigate the in vivo synergy between romidepsin and cytarabine ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• July 2019

Public health measures targeting coronavirus disease 2019 have potential to impact transmission of other respiratory viruses. We found 98.0% and 99.4% reductions in respiratory syncytial virus and influenza detections, respectively, in Western Australian children through winter 2020 despite schools reopening. Border closures have likely been important in limiting external introductions. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

We suggest that 37 weeks' gestation may not be the optimal cutoff for defining perinatal risk as it applies to behavioural development. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• April 2013

Melissa Fiona Helen Rebecca Peter O'Donnell Stanley Leonard Glauert Jacoby M FJ HM RA PJ BPsych (Hons), MPsych, GradDip Ed, PhD FAA FASSA MSc MD FFPHM FAFPHM FRACP FRANZCOG HonDSc HonDUniv HonFRACGP HonMD HonFRCPCH HonLLB (honoris causa) MBChB MPH ...

• Telethon Kids Institute
• Projects