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        International trends of Down syndrome 1993-2004: Births in relation to maternal age and terminations of pregnancies

        The aim of this study was to examine trends of Down syndrome (DS) in relation to maternal age and termination of pregnancies (ToP) in 20 registries ...

        Research

        Toward improved prediction of risk for atopy and asthma among preschoolers: A prospective cohort study

        Atopy and asthma are commonly initiated during early life, and there is increasing interest in the development of preventive treatments for at-risk children. ...

        Research

        Inner speech impairment in children with autism is associated with greater nonverbal than verbal skills

        We present a new analysis of Whitehouse, Maybery, and Durkin's (2006, Experiment 3) data on inner speech in children with autism (CWA). ...

        Research

        A systematic review of prevention interventions to reduce prenatal alcohol exposure and fetal alcohol spectrum disorder in Indigenous communities

        Liz Martyn Milne Symons E MS MPH PhD B.A. (Hons) PhD. Honorary Emeritus Fellow Honorary Research Associate 08 6319 1672 martyn.symons@telethonkids.org.au Honorary Emeritus Fellow Postdoctoral Researcher Liz is an epidemiologist specialising in the ...

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        Ear Portal: An ENT and Audiology referral portal for improving access to ear health services for children using telehealth

        Chris Deborah Peter Tanisha Greta Karina Brennan-Jones Lehmann Richmond Cayley Bernabei Tao C D PC TC GB KT PhD AO, MBBS, MSc MBBS MRCP(UK) FRACP BBiomed (Hons) BSc B.SpLPath&Aud, MClincAud, PhD Head, Ear Health Honorary Emeritus Fellow Head, ...

        Research

        Tracking global intervention coverage

        Adam Dan Saddler Weiss AS DW PhD PhD Research Officer Honorary Research Fellow Daniel.Weiss@telethonkids.org.au Research Officer Honorary Research Fellow Adam is experienced in mosquito control interventions and mosquito ecology. He holds a PhD in ...

        Research

        Romidepsin enhances the efficacy of cytarabine in vivo, revealing HDAC inhibition as a therapeutic strategy for KMT2A-rearranged acute lymphoblastic leukemia

        In this study, we investigate the in vivo synergy between romidepsin and cytarabine ...

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        Hospital admissions in children with developmental disabilities from ethnic minority backgrounds

        Children with CP and intellectual disability, particularly from minority backgrounds, were at higher risk of being admitted to hospital after the first year of life ...

        Research

        Pets Are Associated with Fewer Peer Problems and Emotional Symptoms, and Better Prosocial Behavior: Findings from the Longitudinal Study of Australian Children

        Pets may protect children from developing social-emotional problems and should be taken into account when assessing child development and school readiness ...

        Research

        Impact of Coronavirus Disease 2019 Public Health Measures on Detections of Influenza and Respiratory Syncytial Virus in Children During the 2020 Australian Winter

        Public health measures targeting coronavirus disease 2019 have potential to impact transmission of other respiratory viruses. We found 98.0% and 99.4% reductions in respiratory syncytial virus and influenza detections, respectively, in Western Australian children through winter 2020 despite schools reopening. Border closures have likely been important in limiting external introductions. ...

        Research

        Developmental Origins of Health and Disease (DOHaD): The importance of life-course and transgenerational approaches

        With well-established evidence that early life conditions have a profound influence on lifespan and health-span, new interventional birth cohorts are examining ways to optimise health potential of individuals and communities. These are aimed at going beyond preventing disease, to the conditions that facilitate flourishing from an early age. ...

        Research

        Exploring quality of life in individuals with a severe developmental and epileptic encephalopathy, CDKL5 Deficiency Disorder

        CDKL5 Deficiency Disorder (CDD) is a rare genetic disorder caused by a mutation in the cyclin-dependent kinase-like 5 (CDKL5) gene. It is now considered to be a developmental and epileptic encephalopathy because of the early onset of seizures in association with severe global delay. Other features include cortical visual impairment, sleep and gastro-intestinal problems. Progress in clinical understanding, especially regarding the spectrum of functional ability, seizure patterns, and other comorbidities was initially slow but accelerated in 2012 with the establishment of the International CDKL5 Database (ICDD). Our aim was to use this data source to investigate quality of life (QOL) and associated factors in this disorder. ...

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