Severity and disease progression in people with Cystic Fibrosis is typically dependent on their genotype. One potential therapeutic strategy for people with specific mutations is exon skipping with antisense oligonucleotides. CFTR exon 9 is an in-frame exon and hence the exclusion of this exon would excise only 31 amino acids but not alter the reading frame of the remaining mRNA. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• March 2022

Omega fatty acids are essential for young children’s growth and development. They also have essential functions in cell receptors of membranes and regulation of hormones synthesis. Essential fatty acids such as omega-3 and -6 can only be obtained through food mainly fish and other seafood and to a lesser extent through nuts, seeds, and plant oils. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• January 2023

Abdominal aortic aneurysm (AAA) has been recognized as a multi-factorial disease with both genetic and environmental risk factors. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• October 2010

Emma Adams EA BExSc, MPH Acting Research Officer -Playce, Research Assistant & PhD student Emma.Adams@telethonkids.org.au Research Assistant, PhD student Emma has been at the Telethon Kids Institute since 2017 and is currently a Research Assistant ...

• 1. Telethon Kids Institute
• Projects
• The ARC Centre of Excellence for Children and Families over the Life Course

Policies aiming to improve educational outcomes are typically based on academic testing data. However, such data only reflects those who complete the test. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• January 2017

The meningococcal serogroup B-factor H binding protein vaccine (MenB-FHbp) is licensed for use in children aged 10 years or older for protection against invasive serogroup B meningococcal disease. Because young children are at increased risk of invasive meningococcal disease, MenB-FHbp clinical data in this population are needed. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• January 2023

History of the exploration of human growth ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• July 2011

Authors: Maple-Brown LJ, Sinha AK, Davis EA. Authors notes: J Paediatr Child Health. 2010 Sep;46(9):487-90. doi: 10.1111/j.1440-1754.2010.01844.x. Keywords: Type 2 diabetes, Indigenous Australian children, adolescents Abstract: Rates of type 2 ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• September 2010

To evaluate the safety and immunogenicity of V114 [15-valent pneumococcal conjugate vaccine (PCV) containing serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9 V, 14, 18C, 19A, 19F, 22F, 23F, 33F], followed by 23-valent pneumococcal polysaccharide vaccine (PPSV23) 8 weeks later, in children with HIV. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023

Otitis media is a common childhood illness associated with hearing loss, social disadvantage and medical costs. Prevalence and severity are high among... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2009
• November 2009

We aimed to determine whether myeloperoxidase (MPO) is the main peroxidase present in the airways of children with cystic fibrosis (CF) and to assess which oxid ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• November 2010

Cytokines in milk like transforming growth factor-beta (TGF-beta) have been shown to induce oral tolerance in experimental animal studies ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• February 2010