The induction of DNA damage has been employed as an anticancer strategy for more than 100years, first starting with the use of radiation to treat stomach cancer followed by the first uses of DNA-damaging chemotherapy to treat childhood leukemia. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• January 2022

Delivering cancer control at scale for Aboriginal and Torres Strait Islander communities is a national priority that requires Aboriginal and Torres Strait Islander leadership and codesign, as well as significant involvement of the Aboriginal community-controlled health sector. The unique genomic variation observed among Aboriginal and Torres Strait Islander peoples may have implications for standard and precision medicine. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• July 2024

This chapter provides an update on the latest findings in the role of the gut microbiota in cancer. Herein we discuss how the composition and the diversity of the gut microbiota result in the latter to function as a tumour-suppressor, a tumour-promoter or an aid in the recovery post cancer treatment. © 2023 John Wiley & Sons Ltd. All rights reserved. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• September 2023

Raelene Nick Endersby Gottardo R NG BSc (Hons) PhD MBChB FRACP PhD Brainchild Fellow; Co-Head, Brain Tumour Research Co-Head, Brain Tumour Research raelene.endersby@telethonkids.org.au nicholas.gottardo@telethonkids.org.au Co-Head, Brain Tumour ...

• 1. Telethon Kids Institute
• Projects

Timo Lassmann T BSc (Hons) MSc PhD Feilman Fellow; Program Head, Precision Health and Team Lead, Computational Biology timo.lassmann@telethonkids.org.au Feilman Fellow; Program Head, Precision Health and Team Lead, Computational Biology Timo ...

• 1. Telethon Kids Institute
• Our research
• Chronic and Severe Diseases
• Precision Health
• Computational Biology

Background Evidence relating childhood cancer to high birthweight is derived primarily from registry and case-control studies. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

Development of standardised guidance by national and regional authorities for reducing the risk of SARS-CoV-2 transmission to children with cancer ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

Brain cancer and leukemia are the most common cancers diagnosed in the pediatric population and are often treated with lifesaving chemotherapy. However, chemotherapy causes severe adverse effects and chemotherapy-induced peripheral neuropathy (CIPN) is a major dose-limiting and debilitating side effect. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• October 2022

In this sub-study, we aimed to investigate factors that may have influenced study participation and completeness of survey completion. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• May 2013

The risks of adverse obstetric outcomes among young women survivors of colorectal cancer (CRC) are uncertain. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• July 2013

Research has shown differences in how fathers and mothers respond to a child's cancer diagnosis. Previous studies have highlighted that sociocultural norm shape fathers' experiences of their child's cancer diagnosis. Our phenomenological qualitative study aimed to examine the lived experiences of fathers whose children have been diagnosed with cancer and explore the impact of sociocultural gender roles. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• January 2023

In this review, we discuss the different subsets of tumor-infiltrating dendritic cells and their role in anti-tumor immunity ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• April 2019