Benzathine penicillin G (BPG) has been in use since the 1950s for treatment of skin infections, bacterial pharyngitis, syphilis and prevention of recurrent episodes of acute rheumatic fever (ARF).  Current guidelines recommend BPG every 4 weeks for ...

• 1. Telethon Kids Institute
• Projects

Reliable supplies of BPG are essential for delivering the recommended schedule of secondary prophylaxis for people living with RHD. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• August 2015

Jonathan Carapetis AM JR AM MBBS FRACP FAFPHM PhD FAHMS Executive Director; Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@telethonkids.org.au Institute Director; Head, Strep A Translation; Co-Founder of REACH Professor ...

• 1. Telethon Kids Institute
• Projects
• Penicillin Program

Jonathan Rosemary Carapetis AM Wyber JR R AM MBBS FRACP FAFPHM PhD FAHMS MBChB MPH FRACGP PhD Executive Director; Head, Strep A Translation; Co-Founder of REACH Senior Research Fellow 08 6319 1000 contact@telethonkids.org.au Institute Director; Head ...

• 1. Telethon Kids Institute
• Projects

Jonathan Tim Carapetis AM Barnett JR TB AM MBBS FRACP FAFPHM PhD FAHMS PhD Executive Director; Head, Strep A Translation; Co-Founder of REACH Head of the Strep A Pathogenesis & Diagnostics team, Deputy Director of the Wesfarmers Centre of Vaccines ...

• 1. Telethon Kids Institute
• Projects

Benzathine penicillin G (BPG) is used as first-line treatment for most forms of syphilis and as secondary prophylaxis against rheumatic heart disease (RHD). Perceptions that poor quality of BPG is linked to reported adverse effects and therapeutic failure may impact syphilis and RHD control programs. Clinical networks and web-based advertising were used to obtain vials of BPG from a wide range of countries. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• December 2020

These results indicate that anaphylaxis is not a major cause of adverse reactions to benzathine penicillin G ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• June 2019

Asha Jonathan Bowen Carapetis AM AC JR BA MBBS DCH FRACP PhD GAICD AM MBBS FRACP FAFPHM PhD FAHMS Team Lead, Healthy Skin and ARF Prevention Executive Director; Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@telethonkids.org.au ...

• 1. Telethon Kids Institute
• Projects
• Penicillin Program

Penicillin allergy accounts for the majority of all reported adverse drug reactions in adults and children. Foregoing first-line antibiotic therapy due to penicillin allergy label is associated with an increased prevalence of infections by resistant organisms and longer hospitalisation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• May 2022

Benzathine penicillin G availability should be addressed and African health workers’ knowledge and practices need to be augmented ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• November 2019

Jonathan Rosemary Carapetis AM Wyber JR R AM MBBS FRACP FAFPHM PhD FAHMS MBChB MPH FRACGP PhD Executive Director; Head, Strep A Translation; Co-Founder of REACH Senior Research Fellow 08 6319 1000 contact@telethonkids.org.au Institute Director; Head ...

• 1. Telethon Kids Institute
• Projects
• Penicillin Program

Acute rheumatic fever (ARF), a serious inflammatory condition, often leads to rheumatic heart disease. Between 2011 and 2016, Aotearoa New Zealand implemented a rheumatic fever prevention programme to reduce high rates of ARF through improved community access to timely diagnosis and early treatment of group A streptococcal pharyngitis, which has been shown to prevent subsequent ARF. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• December 2023