Rheumatic heart disease affects more than 40.5 million people worldwide and results in 306,000 deaths annually. Echocardiographic screening detects rheumatic heart disease at an early, latent stage. Whether secondary antibiotic prophylaxis is effective in preventing progression of latent rheumatic heart disease is unknown. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• January 2022

Few children and adolescents receiving BPG as secondary prophylaxis will achieve concentrations >0.02 mg/L for the majority of the time between injections ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• July 2019

Benzathine penicillin G availability should be addressed and African health workers’ knowledge and practices need to be augmented ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• November 2019

This retrospective study assessed maternal and perinatal outcomes for women with rheumatic heart disease admitted to the largest tertiary obstetric hospital ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• April 2020

This study was designed to determine the sensitivity and reproducibility of recovering anti-streptolysin O titres (ASOT) from dried blood spot (DBS) samples ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• September 2017

This review outlines a clinical development strategy detailing the phases of development required for registration of a candidate Group A streptococci vaccin ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• April 2017

We aimed to review RHD burden in Western Pacific Region outside Oceania to identify countries with high RHD burden ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• January 2017

Adverse outcomes for people with acute rheumatic fever and rheumatic heart disease and the effect of comorbidities and demographic factors on these outcomes ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• July 2016

Sensitivity and positive predictive value of cardiac auscultation compared with echocardiography is poor, regardless of the expertise of the auscultator. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• August 2013

We aimed to measure the incidence and severity of invasive Group A Strep disease in the NT since 1996. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• January 2014

The association between group A streptococcal infection and rheumatic fever (RF) was established in the early 20th century. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• May 2015

Reliable supplies of BPG are essential for delivering the recommended schedule of secondary prophylaxis for people living with RHD. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• August 2015