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        Research

        Epigenetic Age Acceleration in Adolescence Associates with BMI, Inflammation, and Risk Score for Middle Age Cardiovascular Disease

        Accelerated epigenetic age in adolescence was associated with inflammation, BMI measured 5 years later, and probability of middle age cardiovascular disease ...

        Research

        Severity Assessment in CDKL5 Deficiency Disorder

        A severity assessment was rapidly developed with input from multiple stakeholders. Refinement through ongoing validation is required for future clinical trials. ...

        Research

        Most clinical anti-EGFR antibodies do not neutralize both wtEGFR and EGFRvIII activation in glioma

        We discovered a previously unknown major resistance mechanism in glioma in that most EGFR domain III-targeting antibodies do not neutralize EGFRvIII ...

        Research

        An urgent need for antimicrobial stewardship in Indigenous rural and remote primary health care

        We write this perspective to raise awareness of antimicrobial resistance as an issue in Indigenous primary health care ...

        Research

        Developmental vitamin D deficiency produces behavioral phenotypes of relevance to Autism in an animal model

        Here we investigate these features in an animal model related to autism spectrum disorder - the DVD-deficient rat ...

        Research

        Single-breath washout and association with structural lung disease in children with cystic fibrosis

        Acinar ventilation inhomogeneity measured by single-breath washout was not associated with structural lung disease on CT ...

        Research

        Survival and mortality in cerebral palsy: Observations to the sixth decade from a data linkage study of a total population register and National Death Index

        Since 1990 mortality for those with severe cerebral palsy in Western Australia has tended to shift from childhood to early adulthood ...

        Research

        Influenza vaccine effectiveness in preventing influenza-associated hospitalizations during pregnancy: A multi-country retrospective test negative design study, 2010–2016

        Between 2010 and 2016, influenza vaccines offered moderate protection against laboratory-confirmed influenza-associated hospitalizations during pregnancy ...

        Research

        Impact of heart disease on maternal, fetal and neonatal outcomes in a low-resource setting

        Occult maternal heart disease may be responsible for a substantial proportion of adverse pregnancy outcomes in low-resource settings ...

        Research

        Viewpoints on what is important to maintain relationship satisfaction in couples raising a child with autism spectrum disorder

        Couples should be supported to strengthen communication processes and work in partnership to raise their child with ASD through family-centred interventions ...

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