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        Research

        Unusual paediatric spinal myxopapillary ependymomas: Unique molecular entities or pathological variations on a theme?

        We describe two unusual cases of MPE and use DNA methylation analyses to compare their signatures to try and distinguish if these represent a unique subset. ...

        Research

        High Dose Vitamin D supplementation alters faecal microbiome and predisposes mice to more severe colitis

        High dose vitamin D supplementation is associated with a shift to a more inflammatory faecal microbiome and increased susceptibility to colitis ...

        Research

        Mucormycosis in Children: Review and Recommendations for Management

        we summarize the literature on the epidemiology and diagnosis of this invasive fungal infection and provide suggestions on the management of mucormycosis in children ...

        Research

        Larger Than Life: Injecting Hope into the Planetary Health Paradigm

        We argue that the success of planetary health solutions is predicated on a more sophisticated understanding of the psychology of prevention and intervention at all scales ...

        Research

        Foetal growth restriction in mice modifies postnatal airway responsiveness in an age and sex-dependent manner

        Our data demonstrate changes in airway responsiveness as a result of intrauterine growth restriction that could influence susceptibility to asthma development ...

        Research

        Medulloblastoma

        Medulloblastoma is a highly malignant small round blue cell tumor of the posterior fossa ...

        Research

        Group A streptococcal pharyngitis: Immune responses involved in bacterial clearance and GAS-associated immunopathologies

        Innate and adaptive host immune responses are fundamental for defense against streptococcal pharyngitis and are central to the clinical manifestation of disease. ...

        Research

        Endocrine and metabolic consequences due to restrictive carbohydrate diets in children with type 1 diabetes: An illustrative case series

        The promotion of a low carbohydrate diet in media is in contrast to published pediatric diabetes guidelines that endorse a balanced diet from a variety of foods ...

        Research

        Telehealth for Diagnosis of Hearing Loss

        Telehealth offers unique opportunities for providing access to hearing healthcare ser- vices to underserved populations ...

        Research

        Investment in child and adolescent health and development: key messages from Disease Control Priorities, 3rd Edition

        The realisation of human potential for development requires age-specific investment throughout the 8000 days of childhood and adolescence. ...

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